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Withdrawal Interval (WDI) Recommendations

for swine, taken from the FARAD Digests

WARNING!

Extra Label Use of this drug is permissible under AMDUCA only if such use is by or on the lawful written or oral order of a licensed veterinarian within the context of a valid veterinarian-client-patient relationship.


Below are the WDI recommendations for the various route and dosage combination(s) for extra-label administration of in swine.

 

Drug Route Dosage Frequency Meat WDI
acepromazine IV up to 0.055 mg/kg single and multiple doses 7 days
acepromazine Reference(s): Extralabel use of tranquilizers and general anesthetics
activated charcoal PO n.a. n.a. 0 days
activated charcoal Reference(s): Antidotes in food animal practice
atropine IV up to 0.2 mg/kg every 4-6 hours 28 days
atropine Warnings: treatment of organophosphate toxicosis; be sure there are no organophosphates residues
atropine Reference(s): Antidotes in food animal practice
atropine
atropine IM up to 0.2 mg/kg every 4-6 hours 28 days
atropine Warnings: treatment of organophosphate toxicosis; be sure there are no organophosphates residues
atropine Reference(s): Antidotes in food animal practice
atropine
atropine SC up to 0.2 mg/kg every 4-6 hours 28 days
atropine Warnings: treatment of organophosphate toxicosis; be sure there are no organophosphates residues
atropine Reference(s): Antidotes in food animal practice
epinephrine SC n.a. multiple doses 0 days
epinephrine Warnings: endogenous substance with rapid metabolism
epinephrine Reference(s): Antidotes in food animal practice
epinephrine
epinephrine IV n.a. multiple doses 0 days
epinephrine Warnings: endogenous substance with rapid metabolism
epinephrine Reference(s): Antidotes in food animal practice
epinephrine
epinephrine IM n.a. multiple doses 0 days
epinephrine Warnings: endogenous substance with rapid metabolism
epinephrine Reference(s): Antidotes in food animal practice
flunixin meglumine IM 2.2 mg/kg single dose 13-15 days
flunixin meglumine Warnings: non-swine labeled formulation
flunixin meglumine Reference(s): Avoiding violative flunixin meglumine residues in cattle and swine
flunixin meglumine
flunixin meglumine IV 2.2 mg/kg multiple doses 21 days
flunixin meglumine Reference(s): Avoiding violative flunixin meglumine residues in cattle and swine
flunixin meglumine
flunixin meglumine PO 2.2 mg/kg multiple doses 21 days
flunixin meglumine Reference(s): Avoiding violative flunixin meglumine residues in cattle and swine
ketamine IM up to 10 mg/kg single and multiple doses 2 days
ketamine Reference(s): Extralabel use of tranquilizers and general anesthetics
ketamine
ketamine IV up to 10 mg/kg single and multiple doses 2 days
ketamine Reference(s): Extralabel use of tranquilizers and general anesthetics
pralidoxime (2-PAM) IM up to 30 mg/kg every 8 hours 28 days
pralidoxime (2-PAM) Warnings: treatment of organophosphate toxicosis; be sure there are no organophosphates residues
pralidoxime (2-PAM) Reference(s): Antidotes in food animal practice
procaine penicillin g IM 24,000 units/kg once daily for 5 days 8 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 24,000 units/kg twice daily for 5 days 11 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 33,000 units/kg once daily for 5 days 9 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 33,000 units/kg twice daily for 5 days 14 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 44,000 units/kg once daily for 5 days 11 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 44,000 units/kg twice daily for 5 days 16 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 66,000 units/kg once daily for 5 days 14 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 66,000 units/kg twice daily for 5 days 20 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered Crysticillin, Pro-Pen-G products ONLY. The veterinarian is encouraged to contact FARAD for other animal categories or formulations. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
procaine penicillin g
procaine penicillin g IM 6,600 - 15,000 units/kg up to 3 days every 24 hours 14 days
procaine penicillin g Warnings: This WDI applies to market weight hogs administered with procaine penicillin G products other than Crysticillin or Pro-Pen-G. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site. The veterinarian is encouraged to contact FARAD if more than 3 repeated doses are given.
procaine penicillin g
procaine penicillin g IM up to 33,000 units/kg up to 3 days every 24 hours 38 days
procaine penicillin g Warnings: This WDI applies to heavy sows administered Crysticillin, Pro-Pen-G products ONLY. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site. The veterinarian is encouraged to contact FARAD if more than 3 repeated doses are given.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
Reference(s): An integrated experimental and physiologically based pharmacokinetic modeling study of penicillin G in heavy sows
procaine penicillin g
procaine penicillin g IM 33,000 - 66,000 units/kg, or formulations not listed once daily for 5 days 51 days
procaine penicillin g Warnings: This WDI applies to heavy sows administered non-Crysticillin, Pro-Pen-G products ONLY. Use 18 gauge, 4-cm needles inserted horizontally, caudal to the ear, at the margin of haired and hairless skin, with injection volumes not exceeding 11 ml/site.
procaine penicillin g Reference(s): Update on withdrawal intervals following extralabel use of procaine penicillin G in cattle and swine
Reference(s): Depletion of Penicillin G Residues in Heavy Sows after Intramuscular Injection
vitamin K1 (phytonadione) SC 0.5 - 2.5 mg/kg per label 0 days
vitamin K1 (phytonadione) Reference(s): Antidotes in food animal practice
vitamin K1 (phytonadione)
vitamin K1 (phytonadione) IV 0.5 - 2.5 mg/kg per label 0 days
vitamin K1 (phytonadione) Reference(s): Antidotes in food animal practice
vitamin K1 (phytonadione)
vitamin K1 (phytonadione) IM 0.5 - 2.5 mg/kg per label 0 days
vitamin K1 (phytonadione) Reference(s): Antidotes in food animal practice


If you have further questions or concerns, please contact our ELDU advice team.
Photo by Alamy from US Humane Society website