21. Update on on drugs prohibited from extralabel use in food animals, September 2009
20. Extralabel use of nonsteroidal anti-inflammatory drugs in cattle, March 2008
19. Current update on drugs for game bird species, November 2007
18. Extralabel use of penicillin in food animals, November 2006
17. Effect of formulation and route of administration on tissue residues and withdrawal times, November 2005
16. Aminoglycoside residues in food of animal origin, July 2005
15. Extralabel intramammary use of drugs in dairy cattle, June 2005
14. Antidotes in food animal practice, March 2005
13. Drugs approved for small ruminants, February 2004
12. Current approved drugs for aquatic species, January 2004
11. Evaluation of the advisory services provided by FARAD, December 2003
10. Update on FARAD food animal drug withholding recommendations, November 2003
  9. Extralabel use of ivermectin and moxidectin in food animals, September 2000
  8. Drugs prohibited from extralabel use in food animals, July 1999
  7. Primer on estimating withdrawal times after extralabel drug use, October 1998
  6. Prevention of residues in veal calves fed colostrum from dry-treated cows, July 1998
  5. Non-steroidal anti-inflammatory drugs (NSAID), October 1997
  4. Extralabel use of tranquilizers and general anesthetics, August 1997
  3. Extralabel use of oxytetracycline, July 1997
  2. Residue avoidance after topical application of veterinary drugs and parasiticides, May 1997
  1. Breaking new ground, March 1997

to look up withdrawal interval recommendations published in the FARAD Digests

FARAD Newsletter #13 - December 2009
FARAD Newsletter #11 - July 2008
FARAD Newsletter #10 - December 2007
FARAD Newsletter #9 - June 2007
FARAD Newsletter #8 - January 2007
FARAD Newsletter #7 - July 2006
FARAD Newsletter #6 - January 6, 2006
FARAD Newsletter #5 - amended May 5, 2005
FARAD Newsletter #5 - April 12, 2005
FARAD Newsletter #4 - Clarification
FARAD Newsletter #4 - November 2004
FARAD Newsletter #3 - March 5, 2003
FARAD Newsletter #2 - March 10, 2002
FARAD Newsletter #1 - January 8, 2002

Handbook of Comparative Pharmacokinetics and Residues of Veterinary Antimicrobials, by Jim E. Riviere, Arthur L. Craigmill, and Stephen F. Sundlof. ©CRC Press 1991

Handbook of Comparative Pharmacokinetics and Residues of Veterinary Antimicrobials, by Arthur L. Craigmill, Stephen F. Sundlof, and Jim E. Riviere. ©CRC Press 1994

Handbook of Comparative Pharmacokinetics and Residues of Veterinary Antimicrobials, by Stephen F. Sundlof, Jim E. Riviere, and Arthur L. Craigmill. ©CRC Press 1996

Chemical Food Safety: A Scientist's Perspective by J. Edmond Riviere. ©Wiley, John & Sons, Incorporated 2003

Tabulation of FARAD Comparative and Veterinary Pharmacokinetic Data, by Arthur L. Craigmill, Jim E. Riviere, and Alistair. I. Webb ©Blackwell Publishing 2006

in Chronological Order:

Clothier, K. A., Leavens, T., Griffith, R. W., Wetzlich, S. E., Baynes, R. E., Riviere, J. E., Tell, L. A.: Tulathromycin assay validation and tissue residues after single and multiple subcutaneous injections in domestic goats (Capra aegagrushircus). J. vet. Pharmacol. Therap. 35, 113-120.

Leavens, T. L., Tell, L. A., Clothier, K. A., Griffith, R. W., Baynes, R. E., Riviere, J. E.: Development of a physiologically based pharmacokinetic model to predict tulathromycin distribution in goats. J. vet. Pharmacol. Therap. 35,121–131.

Goetting V, Lee KA, Tell LA: Pharmacokinetics of veterinary drugs in laying hens and residues in eggs: a review of the literature. J Vet Pharmacol Ther. (ePub ahead of print),2011.

Buur JL, Baynes RE, Smith G and Riviere JE: Pharmacokinetics of flunixin meglumine in swine after intravenous dosing. J Vet Pharmacol Ther. 29(5):437-440,2006.

Buur J, Baynes R, Smith G and Riviere J: Use of probabilistic modeling within a physiologically based pharmacokinetic model to predict sulfamethazine residue withdrawal times in edible tissues in swine. Antimicrob Agents Chemother. 50(7): 2344-2351,2006.

Gehring R, Baynes RE, Riviere JE: Application of risk assessment and management principles to the extralabel use of drugs in food-producing animals. J Vet Pharmacol Ther. 29(1):5-14,2006.

Buur JL, Baynes RE, Craigmill AL, Riviere JE: Development of a physiologic-based pharmacokinetic model for estimating sulfamethazine concentrations in swine and application to prediction of violative residues in edible tissues. Am J Vet Res. 66(10):1686-1693,2005.

Gehring R, van der Merwe D, Pierce A, Baynes R, Craigmill A, Riviere JE: Multivariate meta-analysis of pharmacokinetic studies of ampicillin trihydrate in cattle. Am J Vet Res. 66(1):108-112,2005.

Craigmill AL, Miller GR, Gehring R, Pierce AN, Riviere JE: Meta-analysis of pharmacokinetic data of veterinary drugs using the Food Animal Residue Avoidance & Depletion Program: oxytetracycline and procaine. J Vet Pharmacol Ther. 27(5):343-353,2004.

Gehring R, Baynes RE, Wang J, Craigmill AL, Riviere JE: A web-based decision support system to estimate extended withdrawal intervals. Computers and Electronics in Agriculture. 44(2):145-151,2004.

Smith GW, Gehring R, Riviere JE, Yeatts JL, Baynes RE: Elimination kinetics of ceftiofur hydrochloride after intramammary administration in lactating dairy cows. J Am Vet Med Assoc. 224(11):1827-1830,2004.

Gehring R, Baynes RE, Craigmill AL, Riviere JE: Feasibility of using half-life multipliers to estimate extended withdrawal intervals following the extralabel use of drugs in food-producing animals. J Food Prot. 67(3):555-560,2004.

in Chronological Order:

Wang J, Gehring R, Baynes RE, Webb AI, Whitford C, Payne MA, Fitzgerald K, Craigmill AL, Riviere JE: Evaluation of the advisory services provided by the Food Animal Residue Avoidance Databank. J Am Vet Med Assoc. 223(11):1596-1598,2003.

Craigmill AL: A physiologically based pharmacokinetic model for oxytetracycline residues in sheep. J Vet Pharmacol Ther. 26(1):55-63,2003.

Martin-Jimenez T, Baynes RE, Craigmill A, Riviere JE: Extrapolated withdrawal-interval estimator (EWE) algorithm: a quantitative approach to establishing extralabel withdrawal times. Regul Toxicol Pharmacol. 36(1):131-137,2002.

Craigmill AL, Cortright KA AAPS: Interspecies considerations in the evaluation of human food safety for veterinary drugs. AAPS PharmSci. 4(4):E34,2004.

Martin-Jimenez T, Riviere JE: Mixed-effects modeling of the interspecies pharmacokinetic scaling of oxytetracycline. J Pharm Sci. 91(2):331-341,2002.

Martin-Jimenez T, Riviere JE: Mixed effects modeling of the disposition of gentamicin across domestic animal species. J Vet Pharmacol Ther. 24(5):321-332,2001.

Baynes RE, Martin-Jimenez T, Craigmill AL, Riviere JE: Estimating provisional acceptable residues for extralabel drug use in livestock. Regul Toxicol Pharmacol. 29(3):287-299,1999.

Payne MA, Craigmill AL, Riviere JE, Baynes RE, Webb AI, Sundlof SF: The Food Animal Residue Avoidance Databank (FARAD). Past, present and future. Vet Clin North Am Food Anim Pract. 15(1):75-88,1999.

Sischo WM, Norman HS, Kiernan NE: Use of the Food Animal Residue Avoidance Databank (FARAD). J Am Vet Med Assoc. 214(3):344-350,1999.

Riviere JE, Martin-Jimenez T, Sundlof SF, Craigmill AL: Interspecies allometric analysis of the comparative pharmacokinetics of 44 drugs across veterinary and laboratory animal species. J Vet Pharmacol Ther. (6):453-463,1997.

Sundlof SF, Craigmill AL, Riviere JE: Use of the food animal residue avoidance databank. J Am Vet Med Assoc. 198(5):816-819,1991.

Sundlof SF, Craigmill AC, Riviere JE: Food Animal Residue Avoidance Databank (FARAD): a pharmacokinetic-based information resource. J Vet Pharmacol Ther. 9(3):237-245,1986.

We regret to inform you that owing to budgetary constraints and rising production costs, FARAD on CD is no longer available. Nevertheless, we encourage you to use either of two on-line resources, which offer increased information
regarding drug use in food animal species:

1) The new and improved version of VetGRAM now provides expanded search strategies for the most up-to-date information on food animal drugs in the U.S.

2) Be sure to check out the all NEW Withdrawal Interval Lookup, which contains a searchable database of recommended
drug withdrawal intervals published over the past twenty years in the FARAD Digests.

Thank you for your interest and continued support of FARAD and the Chemical Food Safety Program.

January 4, 2011