Prohibited Drug List:Diethylstilbestrol (DES) *Lactating (adult) dairy cattle are defined by FDA as dairy cattle 20 months of age or older regardless of whether they are milking or dry. Currently the only sulfonamide available for use in dairy cattle older than 20 months of age is sulfadimethoxine (SDM). In adult dairy cattle this drug may only be used on-label. Administering higher doses or sustained release SDM products is prohibited. Aside from the above AMDUCA list, regulations related to the Pasteurized Milk Ordinance (PMO) prohibit the presence of dimethyl sulfoxide (DMSO) and colloidal silver on dairies. ** Because dipyrone-containing products are not available for either humans or animals, it is not typically included on lists of extralabel prohibitions published by CVM. Old stockpiles of the drug, however, do occasionally surface. Any use of dipyrone in food animals remains a violation of the Food Drug and Cosmetic Act. PHENYLBUTAZONE ADDED TO PROHIBITED LISTEffective May 29, 2003 the Food and Drug Administration (FDA) will prohibit extralabel use of phenylbutazone animal and human drugs in female dairy cattle 20 months of age or older. The FDA is issuing the order based on evidence that extralabel use of phenylbutazone in female dairy cattle 20 months of age or older will likely cause an adverse event in humans. With this action the use of any phenylbutazone in an adult dairy cow becomes a violation of the Food Drug and Cosmetic Act and one of FDA's highest regulatory priorities. The FDA invites written or electronic comments on the order until April 29, 2003.The entire text of the order of prohibition can be viewed at: |